Scientific Publications

Oncology

Frontiers in Oncology: Development and Characterization of a Novel Non-Lytic Cancer Immunotherapy Using a Recombinant Arenavirus Vector Platform (2021)

Nature Communications: Viral vector-mediated reprogramming of the fibroblastic tumor stroma sustains curative melanoma treatment (2021)

Nature Communications: Viral vector-mediated reprogramming of the fibroblastic tumor stroma sustains curative melanoma treatment (2021)

Cell Reports Medicine: Heterologous arenavirus vector prime-boost overrules self-tolerance for efficient tumor-specific CD8 T cell attack (2021)

OncoImmunology: Live-attenuated lymphocytic choriomeningitis virus-based vaccines for active immunotherapy of HPV16-positive cancer (2020)

Immunity:  Expression of the DNA-Binding Factor TOX Promotes the Encephalitogenic Potential of Microbe-Induced Autoreactive CD8+ T Cells (2018)

Nature Communications: Replicating viral vector platform exploits alarmin signals for potent CD8+ T cell-mediated tumour immunotherapy (2017)

Infectious Diseases

Nature Partner Journals Vaccines: Immunogenic arenavirus vector SIV vaccine reduces setpoint viral load in SIV-challenged rhesus monkeys (2023)

The Journal of Infectious Diseases: Alternating Arenavirus Vector Immunization Generates Robust Polyfunctional Genotype Cross-Reactive Hepatitis B Virus–Specific CD8 T-Cell Responses and High Anti–Hepatitis B Surface Antigen Titers (2023)

International Journal of Molecular Sciences: Replication-Deficient Lymphocytic Choriomeningitis Virus-Vectored Vaccine Candidate for the Induction of T Cell Immunity against Mycobacterium tuberculosis (2022)

The Journal of Infectious Diseases: A Randomized Dose-Escalating Phase I Trial of a Replication-Deficient Lymphocytic Choriomeningitis Virus Vector-Based Vaccine Against Human Cytomegalovirus (2020)

Clinical and Vaccine Immunology: Congenital cytomegalovirus: a “now” problem—no really, now (2017)

Vaccine: Development of novel replication-defective lymphocytic choriomeningitis virus vectors expressing SIV antigens (2017)

Clinical and Vaccine Immunology: Additive protection against congenital cytomegalovirus conferred by combined glycoprotein B/pp65 vaccination using a lymphocytic choriomeningitis virus vector (2017)

Vaccine: Replication-defective lymphocytic choriomeningitis virus vectors expressing guinea pig cytomegalovirus gB and pp65 homologs are protective against congenital guinea pig cytomegalovirus infection (2016)

Journal of Virology: Gene-based vaccination with a mis-matched envelope protects against simian immunodeficiency virus infection in non-human primates (2012)

Nature Medicine: Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity (2010)

Arenavirus Platform / Technology

Molecular Therapy: Recombinant LCMV Vectors Induce Protective Immunity following Homologous and Heterologous Vaccinations (2017)

PLoS Pathogens: Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection. (2015)

Science: The alarmin interleukin-33 drives protective antiviral CD8⁺ T cell responses (2012)